David J Webb Selected Research

Inflammation (Inflammations)

12/2016	Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction.
3/2015	Endothelin in nondiabetic chronic kidney disease: preclinical and clinical studies.
1/2014	Blood markers of coagulation, fibrinolysis, endothelial dysfunction and inflammation in lacunar stroke versus non-lacunar stroke and non-stroke: systematic review and meta-analysis.
5/2011	Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity.
9/2008	Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition.
4/2004	Adenoviral gene delivery of elafin and secretory leukocyte protease inhibitor attenuates NF-kappa B-dependent inflammatory responses of human endothelial cells and macrophages to atherogenic stimuli.

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David J Webb Research Topics

Disease

41	Hypertension (High Blood Pressure) 01/2022 - 09/2002
25	Chronic Renal Insufficiency 10/2021 - 04/2006
16	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 05/2002
9	Proteinuria 01/2019 - 07/2009
8	Heart Failure 04/2021 - 06/2003
7	Pulmonary Arterial Hypertension 01/2019 - 08/2008
7	Atherosclerosis 05/2015 - 01/2007
6	Type 2 Diabetes Mellitus (MODY) 01/2020 - 09/2006
6	Fibrosis (Cirrhosis) 02/2017 - 02/2004
6	Inflammation (Inflammations) 12/2016 - 04/2004
6	Pulmonary Hypertension 03/2013 - 08/2002
5	Acute Kidney Injury (Acute Renal Failure) 04/2021 - 02/2013
5	Kidney Diseases (Kidney Disease) 01/2021 - 09/2009
5	Diabetic Nephropathies (Diabetic Nephropathy) 01/2021 - 11/2007
5	Poisoning 05/2019 - 09/2011
5	Necrosis 10/2017 - 03/2007
5	Epilepsy (Aura) 01/2016 - 02/2005
5	Essential Hypertension 08/2015 - 08/2002
5	Coronary Artery Disease (Coronary Atherosclerosis) 08/2007 - 08/2002
4	Atherosclerotic Plaque (Atheroma) 01/2011 - 04/2004
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019 - 11/2006
3	Portal Hypertension 10/2012 - 02/2004
3	Vascular System Injuries 07/2012 - 03/2003
3	Erectile Dysfunction 03/2008 - 09/2002
2	Pancreatitis 04/2021 - 04/2021
2	Infections 04/2021 - 04/2004
2	Pancreatic Neoplasms (Pancreatic Cancer) 04/2021 - 02/2012
2	Vasculitis (Vasculitides) 01/2021 - 01/2019
2	Drug-Related Side Effects and Adverse Reactions 05/2019 - 12/2007
2	Stroke (Strokes) 01/2018 - 01/2014
2	Diabetes Mellitus 01/2018 - 08/2015
2	Neoplasms (Cancer) 01/2018 - 02/2012
2	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 11/2016 - 12/2013
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2016 - 10/2013
2	Disease Progression 03/2015 - 05/2002
2	Anaphylaxis (Anaphylactic Shock) 02/2014 - 04/2013
2	Vomiting 02/2014 - 04/2013
2	Altitude Sickness (Mountain Sickness) 01/2011 - 05/2007
2	Thrombosis (Thrombus) 05/2008 - 12/2005

Drug/Important Bio-Agent (IBA)

24	Endothelins (Endothelin)IBA 01/2021 - 08/2002
19	Endothelin-1 (Endothelin 1)IBA 12/2021 - 08/2002
14	Endothelin Receptor AntagonistsIBA 01/2021 - 08/2002
9	SodiumIBA 12/2021 - 12/2006
9	Biomarkers (Surrogate Marker)IBA 01/2017 - 02/2004
9	Endothelin A ReceptorIBA 03/2015 - 08/2002
8	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2022 - 09/2011
8	Sildenafil Citrate (Viagra)FDA Link 08/2015 - 10/2004
7	Endothelin Receptors (Endothelin Receptor)IBA 01/2019 - 06/2003
6	Pharmaceutical PreparationsIBA 01/2021 - 08/2015
6	DiureticsIBA 09/2017 - 08/2015
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2013 - 05/2002
5	Antihypertensive Agents (Antihypertensives)IBA 01/2020 - 08/2007
5	LipidsIBA 01/2019 - 04/2004
5	Bosentan (Tracleer)FDA Link 04/2016 - 06/2006
5	CreatinineIBA 08/2015 - 06/2009
5	Uric Acid (Urate)IBA 05/2014 - 11/2006
5	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2014 - 09/2002
5	Phosphodiesterase 5 InhibitorsIBA 03/2013 - 10/2004
4	SaltsIBA 12/2021 - 12/2006
4	Spironolactone (Aldactone)FDA LinkGeneric 10/2021 - 11/2015
4	Endothelin B ReceptorIBA 01/2019 - 08/2006
4	Vasoconstrictor AgentsIBA 02/2017 - 08/2002
4	C-Reactive ProteinIBA 12/2016 - 06/2009
4	Angiotensin Receptor AntagonistsIBA 04/2016 - 02/2004
4	Nifedipine (Adalat)FDA LinkGeneric 03/2015 - 07/2009
3	AtrasentanIBA 12/2021 - 09/2017
3	Chlorthalidone (Chlortalidone)FDA LinkGeneric 10/2021 - 05/2013
3	Peptides (Polypeptides)IBA 01/2021 - 05/2010
3	AntiemeticsIBA 05/2019 - 04/2013
3	Interleukin-6 (Interleukin 6)IBA 12/2016 - 05/2013
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 04/2016 - 06/2004
3	Anticonvulsants (Antiepileptic Drugs)IBA 01/2016 - 02/2005
3	Gabapentin (Neurontin)FDA LinkGeneric 02/2012 - 07/2009
3	Losartan (Cozaar)FDA LinkGeneric 01/2012 - 02/2004
3	sitaxsentanIBA 04/2011 - 11/2007
3	cyclo(Trp-Asp-Pro-Val-Leu)IBA 07/2009 - 08/2002
3	BradykininIBA 01/2008 - 06/2004
2	Glucose (Dextrose)FDA LinkGeneric 04/2021 - 08/2015
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 04/2004
2	Streptozocin (Streptozotocin)FDA Link 01/2019 - 05/2014
2	Amiloride (Midamor)FDA LinkGeneric 01/2018 - 02/2016
2	AldosteroneIBA 01/2018 - 04/2016
2	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2018 - 04/2016
2	ReninIBA 01/2018 - 08/2015
2	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 11/2016 - 12/2013
2	ambrisentan FDA Link 04/2016 - 12/2008
2	CholesterolIBA 02/2015 - 03/2007
2	Acetylcysteine (Siran)FDA LinkGeneric 02/2014 - 02/2012
2	Ondansetron (Zofran)FDA LinkGeneric 02/2014 - 04/2013
2	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2014 - 12/2005
2	HomocysteineIBA 01/2014 - 01/2005
2	Plasminogen InactivatorsIBA 01/2014 - 01/2008
2	AlbuminsIBA 10/2012 - 06/2009
2	Proteins (Proteins, Gene)FDA Link 10/2012 - 04/2011
2	Angiotensin IIIBA 01/2012 - 02/2004
2	Apolipoproteins E (ApoE)IBA 02/2011 - 01/2011
2	Phospholipids (Phosphatides)FDA LinkGeneric 09/2008 - 07/2007
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2008 - 05/2007

Therapy/Procedure

17	Therapeutics 01/2022 - 07/2002
2	Ligation 12/2021 - 02/2011